Package index • CyneRgy

Shared trial operations

GeneratePoissonArrival(): Generate Patient Arrival Times
RandomizationSubjectsUsingUniformDistribution(): Randomize Subjects Between Two Arms
RandomizationSubjectsUsingSampleFunctionInR(): Randomize Subjects to Two Arms Using R's sample() Function
BlockRandomizationSubjectsUsingRPackage(): Permuted Block Randomization for Two-Armed Trials
RandomizeSubjectsAcrossMultipleArms(): Randomize Subjects Across Multiple Arms
GenerateCensoringUsingBinomialProportion(): Generate Dropout Indicators for Binary or Continuous Outcomes

SimulatePatientOutcomePercentAtZero.Binary(): Simulate Binary Patient Outcomes
SimulatePatientOutcomePercentAtZeroBetaDist.Binary(): Simulate Binary Outcomes With Random Structural-Zero Probabilities
AnalyzeUsingPropTest(): Analyze Two-Arm Binary Outcomes With a Proportion Test
AnalyzeUsingPropLimitsOfCI(): Analyze Binary Outcomes Using Confidence-Interval Limits
AnalyzeUsingEastManualFormula(): Analyze Binary Outcomes Using the Manual Test-Statistic Formula
AnalyzeUsingBetaBinomial(): Analyze Binary Data Using a Beta-Binomial Model

SimulatePatientOutcomePercentAtZero(): Simulate Two-Arm Continuous Outcomes
SimulatePatientOutcomePercentAtZeroBetaDist(): Simulate Two-Arm Continuous Outcomes With Random Structural-Zero Probabilities
AnalyzeUsingTTestNormal(): Analyze Two-Arm Continuous Outcomes With a T-Test
AnalyzeUsingMeanLimitsOfCI(): Analyze Continuous Outcomes Using Confidence-Interval Limits
AnalyzeUsingEastManualFormulaNormal(): Analyze Continuous Outcomes Using the Manual Test-Statistic Formula

GenRespDiffOfMeansRepMeasures(): Generate Repeated Measures Responses
GenerateDropoutTimeForRM(): Generate Dropout Times for Repeated Measures Outcomes
Analyze.RepeatedMeasures(): Analyze Repeated Measures Outcomes

SimulatePatientSurvivalWeibull(): Simulate Two-Arm Weibull Survival Outcomes
SimulatePatientSurvivalMixtureExponentials(): Simulate Survival Outcomes From a Mixture of Exponentials
GenerateDropoutTimeForSurvival(): Generate Dropout Times for Survival Outcomes
AnalyzeUsingSurvivalPackage(): Analyze Two-Arm Time-to-Event Outcomes
AnalyzeUsingHazardRatioLimitsOfCI(): Analyze Time-to-Event Outcomes Using Hazard-Ratio Confidence Limits
AnalyzeUsingEastLogrankFormula(): Analyze Time-to-Event Outcomes Using a Log-Rank Formula

SimulatePatientOutcomeDEPSurvBinSingleHazardPiece(): Simulate Correlated Survival and Binary Dual Endpoints
SimulatePatientOutcomeDEPSurvSurvSingleHazardPiece(): Simulate Correlated Survival Dual Endpoints
AnalyzeDEPUsingFisherExact(): Analyze Survival and Binary Dual Endpoints
AnalyzeDEPUsingModWtLogRank(): Analyze Survival Dual Endpoints With a Modestly Weighted Log-Rank Test
GetDEPDecisionsFSD(): Generate Dual-Endpoint Decisions

GeneratePoissonArrivalMEP(): Generate Patient Arrival Times for an MEP Design
GenerateMEPResponse(): Generate Correlated Multiple-Endpoint Responses
GetMEPDecision(): Generate Multiple-Endpoint Decisions

CombineAllRFiles(): Combine All R Files
GetDecisionString(): Generate Decision String Based on Interim and Final Analysis Conditions
GetDecision(): Convert a Decision Label to an Integration Decision Value