Function reference
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AnalyzeUsingBetaBinomial() - Analyze for efficacy using a beta prior to compute the posterior probability that experimental is better than standard of care.
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AnalyzeUsingEastManualFormula() - Compute the statistic using formula 28.2 in the East manual
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AnalyzeUsingEastManualFormulaNormal() - Last Modified Date: 04/18/2024
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AnalyzeUsingHazardRatioLimitsOfCI() - Analyze using a simplified limits of confidence interval design
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AnalyzeUsingMeanLimitsOfCI() - Analyze using a simplified limits of confidence interval design
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AnalyzeUsingPropLimitsOfCI() - Analyze using a simplified limits of confidence interval design.
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AnalyzeUsingPropTest() - Analyze using the prop.test function in base R.
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AnalyzeUsingTTestNormal() - Analyze Using t-test Normal
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CombineAllRFiles() - This function combines the contents of all R files in a specified directory into one file.
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ComputeScaleGivenShapeMedian() - Compute the scale parameter for the Weibull distribution with median = dMedian and scale parameter = dScale
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CreateCyneRgyExample() - Create new CyneRgy example using provided templates. The directory created can be used in connection with Cytel-R integration.
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CreateCyneRgyFunction() - Create a new CyneRgy function using provided templates that can be utilized with R integration points in Cytel products.
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GetDecision() - GetDecision
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InitLoadCyneRgy() - Initialize is used to load required libraries and create any global variables that other integration points need
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ReplaceTagsInFile() - Replace tags in a file.
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RunExample() - Run an example from CyneRgy.
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SelectExpThatAreBetterThanCtrl() - Select treatments that are higher than control or, if none are greater, select the treatment with the largest probability of response.
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SelectExpUsingBayesianRule() - Select treatments to advance based on a Bayesian rule to select any that have at least a user-specified probability of being greater than a user-specified historical response rate.
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SelectExpWithPValueLessThanSpecified() - Compare treatment and experimental to control with a chi-squared test, selecting treatments with a p-value less than specified value. If UserParam is supplied, the list must contain the following named element:
- UserParam$dMaxPValue
A value (0,1) that defines the comparison chi-squared probability for selecting which treatments to advance. Any treatment with less than the specified p-value will be advanced to the second stage
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SelectSpecifiedNumberOfExpWithHighestResponses() - Select user-specified number of treatments to advance that have the largest number of responses.
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SimulatePatientOutcomePercentAtZero() - Simulate patient outcomes from a normal distribution with a percent of patients having an outcome of 0.
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SimulatePatientOutcomePercentAtZeroBetaDist() - Simulate patient outcomes from a normal distribution with a percent of patients having an outcome of 0 where the probability of a 0 is drawn from a Beta distribution.
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SimulatePatientSurvivalMixtureExponentials() - This function simulates from exponential, just included as a simple example as a starting point.
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SimulatePatientSurvivalWeibull() - Simulate patient outcomes from a Weibull distribution.