Generate Decision String Based on Interim and Final Analysis Conditions

This function evaluates look information, efficacy conditions, and futility conditions to generate the decision string (strDecision) required for the GetDecision function. If LookInfo is not NULL, the LookInfo$RejType parameter can be used to determine the design type.

LookInfo$RejType Codes:

• Efficacy Only:

  • 1-Sided Efficacy Upper = 0

  • 1-Sided Efficacy Lower = 2

• Futility Only:

  • 1-Sided Futility Upper = 1

  • 1-Sided Futility Lower = 3

• Efficacy and Futility:

  • 1-Sided Efficacy Upper and Futility Lower = 4

  • 1-Sided Efficacy Lower and Futility Upper = 5

• Not in East Horizon Explore Yet:

  • 2-Sided Efficacy Only = 6

  • 2-Sided Futility Only = 7

  • 2-Sided Efficacy and Futility = 8

  • Equivalence = 9

Usage

GetDecisionString(
  LookInfo,
  nLookIndex,
  nQtyOfLooks,
  bIAEfficacyCondition = FALSE,
  bIAFutilityCondition = FALSE,
  bFAEfficacyCondition = FALSE,
  bFAFutilityCondition = FALSE
)

Arguments

LookInfo

List containing look information passed from East Horizon Explore to the R integration for analysis.

nLookIndex

Integer indicating the current look index, created by the user in the analysis code.

nQtyOfLooks

Integer indicating the total number of looks in the study, created by the user in the analysis code.

bIAEfficacyCondition

Logical condition evaluated to determine interim efficacy at a look (defaults to FALSE).

bIAFutilityCondition

Logical condition evaluated to determine interim futility at a look (defaults to FALSE).

bFAEfficacyCondition

Logical condition evaluated to determine final efficacy at the last look (defaults to FALSE).

bFAFutilityCondition

Logical condition evaluated to determine final futility at the last look (defaults to FALSE).